BDBM26266 Ambien::CHEMBL911::Dalparan::N,N-dimethyl-2-[6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-yl]acetamide::ZPM::Zolpidem::Zolpidem tartrate

SMILES CN(C)C(=O)Cc1c(nc2ccc(C)cn12)-c1ccc(C)cc1

InChI Key InChIKey=ZAFYATHCZYHLPB-UHFFFAOYSA-N

Data  132 KI  8 IC50  1 Kd  7 EC50

PDB links: 4 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 31 hits for monomerid = 26266   

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Universidad De Sevilla

Curated by PDSP K_i Database

LigandBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)Copy SMILESCopy InChI

Affinity DataKi:  5nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankKEGGPC cidPC sidPDBPatentsSimilars

In DepthDetails PubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Universidad De Sevilla

Curated by PDSP K_i Database

LigandBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)Copy SMILESCopy InChI

Affinity DataKi:  5nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankKEGGPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Universidad De Sevilla

Curated by PDSP K_i Database

LigandBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)Copy SMILESCopy InChI

Affinity DataKi:  9.30nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankKEGGPC cidPC sidPDBPatentsSimilars

In DepthDetails PubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Universidad De Sevilla

Curated by PDSP K_i Database

LigandBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)Copy SMILESCopy InChI

Affinity DataKi:  10.3nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankKEGGPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Universidad De Sevilla

Curated by PDSP K_i Database

LigandBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)Copy SMILESCopy InChI

Affinity DataKi:  11.2nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankKEGGPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Universidad De Sevilla

Curated by PDSP K_i Database

LigandBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)Copy SMILESCopy InChI

Affinity DataKi:  12.6nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankKEGGPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Universidad De Sevilla

Curated by PDSP K_i Database

LigandBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)Copy SMILESCopy InChI

Affinity DataKi:  13nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankKEGGPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Universidad De Sevilla

Curated by PDSP K_i Database

LigandBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)Copy SMILESCopy InChI

Affinity DataKi:  13.5nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankKEGGPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Palack£

Curated by ChEMBL

LigandBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)Copy SMILESCopy InChI

Affinity DataKi:  20nMAssay Description:Inhibition of GABAA receptor alpha1 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankKEGGPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedDrugBank
PDB3D Structure (crystal)
Copy BDB DOI

TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Palack£

Curated by ChEMBL

LigandBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)Copy SMILESCopy InChI

Affinity DataKi:  20nMAssay Description:Inhibition of GABAA receptor alpha1 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankKEGGPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedDrugBank
PDB3D Structure (crystal)
Copy BDB DOI

TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Palack£

Curated by ChEMBL

LigandBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)Copy SMILESCopy InChI

Affinity DataKi:  20.7nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankKEGGPC cidPC sidPDBPatentsSimilars

In DepthDetails PubMedDrugBank
PDB3D Structure (crystal)
Copy BDB DOI

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Universidad De Sevilla

Curated by PDSP K_i Database

LigandBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)Copy SMILESCopy InChI

Affinity DataKi:  25nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankKEGGPC cidPC sidPDBPatentsSimilars

In DepthDetails PubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Universidad De Sevilla

Curated by PDSP K_i Database

LigandBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)Copy SMILESCopy InChI

Affinity DataKi:  26nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankKEGGPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Universidad De Sevilla

Curated by PDSP K_i Database

LigandBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)Copy SMILESCopy InChI

Affinity DataKi:  27nMAssay Description:Displacement of [3H]RO15-1788 from recombinant rat GABAalpha1 receptor expressed in HEK293 cells after 1 hrMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankKEGGPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Universidad De Sevilla

Curated by PDSP K_i Database

LigandBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)Copy SMILESCopy InChI

Affinity DataKi:  29.6nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankKEGGPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Palack£

Curated by ChEMBL

LigandBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)Copy SMILESCopy InChI

Affinity DataKi:  41nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankKEGGPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedDrugBank
PDB3D Structure (crystal)
Copy BDB DOI

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Universidad De Sevilla

Curated by PDSP K_i Database

LigandBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)Copy SMILESCopy InChI

Affinity DataKi:  50nMAssay Description:Displacement of [3H]flumazenil from rat GABA-Aalpha1beta2gamma2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankKEGGPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Universidad De Sevilla

Curated by PDSP K_i Database

LigandBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)Copy SMILESCopy InChI

Affinity DataKi:  56.2nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankKEGGPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Palack£

Curated by ChEMBL

LigandBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)Copy SMILESCopy InChI

Affinity DataKi:  112nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankKEGGPC cidPC sidPDBPatentsSimilars

In DepthDetails PubMedDrugBank
PDB3D Structure (crystal)
Copy BDB DOI

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Universidad De Sevilla

Curated by PDSP K_i Database

LigandBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)Copy SMILESCopy InChI

Affinity DataKi:  187nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankKEGGPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Universidad De Sevilla

Curated by PDSP K_i Database

LigandBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)Copy SMILESCopy InChI

Affinity DataKi:  190nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankKEGGPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Universidad De Sevilla

Curated by PDSP K_i Database

LigandBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)Copy SMILESCopy InChI

Affinity DataKi:  332nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankKEGGPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Universidad De Sevilla

Curated by PDSP K_i Database

LigandBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)Copy SMILESCopy InChI

Affinity DataKi:  415nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankKEGGPC cidPC sidPDBPatentsSimilars

In DepthDetails PubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Universidad De Sevilla

Curated by PDSP K_i Database

LigandBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)Copy SMILESCopy InChI

Affinity DataKi:  424nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankKEGGPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Universidad De Sevilla

Curated by PDSP K_i Database

LigandBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)Copy SMILESCopy InChI

Affinity DataKi:  616nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankKEGGPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Universidad De Sevilla

Curated by PDSP K_i Database

LigandBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)Copy SMILESCopy InChI

Affinity DataKi:  622nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankKEGGPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Universidad De Sevilla

Curated by PDSP K_i Database

LigandBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)Copy SMILESCopy InChI

Affinity DataKi:  767nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankKEGGPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Palack£

Curated by ChEMBL

LigandBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)Copy SMILESCopy InChI

Affinity DataIC50:  14nMAssay Description:Inhibition of [3H]-Flumazenil binding to recombinant GABA-A receptor alpha-1 subunit in cerebellumMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankKEGGPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticleDrugBank
PDB3D Structure (crystal)
Copy BDB DOI

TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Palack£

Curated by ChEMBL

LigandBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)Copy SMILESCopy InChI

Affinity DataEC50:  198nMAssay Description:Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 1More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankKEGGPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedDrugBank
PDB3D Structure (crystal)
Copy BDB DOI

TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Palack£

Curated by ChEMBL

LigandBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)Copy SMILESCopy InChI

Affinity DataEC50:  191nMAssay Description:Activity at rat wild type GABAA alpha1beta2gamma2 receptor expressed in xenopus oocytes assessed as GABA-elicited response by two electrode voltage c...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankKEGGPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedDrugBank
PDB3D Structure (crystal)
Copy BDB DOI

TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Palack£

Curated by ChEMBL

LigandBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)Copy SMILESCopy InChI

Affinity DataIC50:  130nMAssay Description:Compound was evaluated for in vitro functional inhibitory potency for prevention of sarafotoxin S6c induced constriction of rat tracheal rings (ETB r...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankKEGGPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticleDrugBank
PDB3D Structure (crystal)
Copy BDB DOI